We aimed to find out how magnesium chloride influences liver health and oxidative stress in rats on a high-fat diet.
In our study, groups of rats were fed either a normal diet, a high-fat diet, or a high-fat diet supplemented with magnesium chloride.
We found that those receiving magnesium showed lower levels of liver enzymes and oxidative stress markers compared to the high-fat diet group alone.
This suggests that magnesium chloride could help protect against the harmful effects of a high-fat diet, although its efficacy in humans needs further investigation.
Read More
9
Magnesium-rich DSW reduces cholesterol
Deep sea water modulates blood pressure and exhibits hypolipidemic effects via the AMPK-ACC pathway: an in vivo study.
We examined how deep sea water (DSW), rich in magnesium, influences high cholesterol and blood pressure. In our study, we tested three different dosages of DSW on spontaneous hypertensive rats over eight weeks.
The results were promising; both systolic and diastolic pressures decreased. Specifically, higher doses of DSW significantly lowered serum cholesterol levels and reduced fat accumulation in liver tissues, showing potential protective effects against heart disease.
Overall, our findings suggest that DSW could be a beneficial alternative for managing cholesterol and blood pressure.
Read More
9
Deep seawater aids cholesterol reduction
Drinking deep seawater decreases serum total and low-density lipoprotein-cholesterol in hypercholesterolemic subjects.
We explored how drinking deep seawater (DSW), rich in magnesium, impacts cholesterol levels in people with high cholesterol. In a study involving 42 volunteers, participants consumed 1050 mL of DSW, magnesium-fortified water, or reverse osmosis water daily for six weeks. The results were promising: those who drank DSW experienced a notable decrease in total cholesterol and low-density lipoprotein (LDL) cholesterol over time. Additionally, blood samples revealed that DSW also reduced markers of oxidative stress. This suggests that DSW may offer a valuable option for managing high cholesterol.
Read More
Most Useful Reviews
9
Cramps eliminated
4 people found this helpful
My wife and I take two tablets before bed. They effectively eliminate our cramps without relying on high-carb bananas. We highly recommend this approach!
Read More
7.5
Reduced triglycerides
2 people found this helpful
I started this for my blood pressure, and positively, my cholesterol and triglyceride levels have also decreased alongside the blood pressure normalising. I'm thrilled with the results.
Read More
9
Blood pressure decrease
1 people found this helpful
My husband began using this supplement after hearing its benefits for reducing high blood pressure. His readings have improved from 148 to 125 after just a few months. The high-quality ingredients have made a significant positive impact, and we plan on purchasing more.
We aimed to find out how magnesium chloride influences liver health and oxidative stress in rats on a high-fat diet.
In our study, groups of rats were fed either a normal diet, a high-fat diet, or a high-fat diet supplemented with magnesium chloride.
We found that those receiving magnesium showed lower levels of liver enzymes and oxidative stress markers compared to the high-fat diet group alone.
This suggests that magnesium chloride could help protect against the harmful effects of a high-fat diet, although its efficacy in humans needs further investigation.
Read More
9
Magnesium-rich DSW reduces cholesterol
Deep sea water modulates blood pressure and exhibits hypolipidemic effects via the AMPK-ACC pathway: an in vivo study.
We examined how deep sea water (DSW), rich in magnesium, influences high cholesterol and blood pressure. In our study, we tested three different dosages of DSW on spontaneous hypertensive rats over eight weeks.
The results were promising; both systolic and diastolic pressures decreased. Specifically, higher doses of DSW significantly lowered serum cholesterol levels and reduced fat accumulation in liver tissues, showing potential protective effects against heart disease.
Overall, our findings suggest that DSW could be a beneficial alternative for managing cholesterol and blood pressure.
Read More
9
Deep seawater aids cholesterol reduction
Drinking deep seawater decreases serum total and low-density lipoprotein-cholesterol in hypercholesterolemic subjects.
We explored how drinking deep seawater (DSW), rich in magnesium, impacts cholesterol levels in people with high cholesterol. In a study involving 42 volunteers, participants consumed 1050 mL of DSW, magnesium-fortified water, or reverse osmosis water daily for six weeks. The results were promising: those who drank DSW experienced a notable decrease in total cholesterol and low-density lipoprotein (LDL) cholesterol over time. Additionally, blood samples revealed that DSW also reduced markers of oxidative stress. This suggests that DSW may offer a valuable option for managing high cholesterol.
Read More
9
4F peptide shows protective effects
Synthetic apolipoprotein A-I mimetic peptide 4F protects hearts and kidneys after myocardial infarction.
We explored the benefits of apolipoprotein A-I mimetic peptide 4F in protecting hearts and kidneys after a heart attack. In our study, male Wistar rats were subjected to a high-cholesterol diet and then induced to have a myocardial infarction.
After receiving 4F or other treatments, we noted that 4F significantly reduced total cholesterol and bad LDL levels while increasing good HDL levels. The results showed 4F was effective in preventing cardiac and renal dysfunction.
Overall, 4F could offer new treatment approaches post-myocardial infarction, promoting heart and kidney health.
Read More
9
Triple therapy effective for hypertension
A Randomized, Multicenter, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and the Tolerability of a Triple Combination of Amlodipine/Losartan/Rosuvastatin in Patients With Comorbid Essential Hypertension and Hyperlipidemia.
We examined a study designed to assess the effectiveness of a triple drug combination—amlodipine, losartan, and rosuvastatin—in patients with both high blood pressure and high cholesterol.
After eight weeks of treatment, those receiving the complete combination showed a significantly greater reduction in LDL cholesterol compared to those on a less intensive regimen.
More importantly, there were no significant tolerability issues reported throughout the study, making this combination a promising option for managing these common health conditions.
My wife and I take two tablets before bed. They effectively eliminate our cramps without relying on high-carb bananas. We highly recommend this approach!
Read More
7.5
Reduced triglycerides
2 people found this helpful
I started this for my blood pressure, and positively, my cholesterol and triglyceride levels have also decreased alongside the blood pressure normalising. I'm thrilled with the results.
Read More
9
Blood pressure decrease
1 people found this helpful
My husband began using this supplement after hearing its benefits for reducing high blood pressure. His readings have improved from 148 to 125 after just a few months. The high-quality ingredients have made a significant positive impact, and we plan on purchasing more.
Read More
7.5
Effective heart support
18 people found this helpful
This dietary supplement has been exceptional for my health. The rapid absorption of magnesium aspartate and potassium has made a noticeable difference. After my course of treatment, the cramps and numbness in my hands vanished. My mood and sleep quality have improved too. This product effectively strengthens the cardiovascular system and can be safely taken without harming other organs. I highly recommend this high-quality supplement for anyone seeking heart health improvement.
Read More
7.5
Lowered blood pressure
10 people found this helpful
Taurine, an amino acid in this product, has been beneficial for my and my daughter's high blood pressure. We're noticing improvements together; my blood pressure has normalised, and now I no longer need medication. The inclusion of magnesium and potassium also supports heart and blood vessel health effectively.
High cholesterol, or hyperlipidemia, is a medical condition characterized by an elevated level of cholesterol in the bloodstream. Cholesterol is a waxy, fat-like substance that’s essential for building healthy cells, but too much of it can lead to serious health issues, including heart disease and stroke. Cholesterol is carried through the blood by lipoproteins, with two main types being low-density lipoprotein (LDL) and high-density lipoprotein (HDL). LDL, often referred to as "bad" cholesterol, can lead to the buildup of plaque in the arteries, while HDL, known as "good" cholesterol, helps carry cholesterol away from the arteries and back to the liver.
Factors contributing to high cholesterol can include poor diet, lack of exercise, obesity, smoking, and genetic predisposition. Regular health screenings are crucial, as high cholesterol often presents no overt symptoms. Maintaining a heart-healthy diet rich in fruits, vegetables, whole grains, and healthy fats, coupled with regular physical activity and avoiding tobacco, can help manage cholesterol levels effectively. In some cases, medications may be necessary to control high cholesterol, so consulting with a healthcare provider is key for tailored advice.
Magnesium is a chemical element with the symbol Mg and atomic number 12. It is a lightweight, silvery-white metal that is a member of the alkaline earth metals group. Often classified as one of the most abundant elements in the Earth's crust, magnesium plays a crucial role in various biological functions and is essential for living organisms. In nature, magnesium can be found in large quantities, primarily in minerals such as dolomite and magnesite, and it is also present in seawater.
In terms of health benefits, magnesium is vital for numerous metabolic processes, including energy production, DNA synthesis, and muscle function. It contributes to bone health, helps regulate blood pressure, and supports bone formation by promoting the effects of vitamin D. The recommended dietary allowance (RDA) for magnesium varies by age and gender, but it is generally important to include magnesium-rich foods like leafy greens, nuts, seeds, and whole grains in your diet to ensure adequate intake. For those who may not receive enough magnesium through their diet alone, supplements are also available; however, it is advisable to consult a healthcare professional before starting any supplementation.
Magnesium plays a crucial role in various bodily functions, including regulating cholesterol levels, but its direct impact on high cholesterol levels is still a topic of ongoing research. Some studies suggest that maintaining adequate magnesium levels can help improve lipid profiles by reducing LDL (bad cholesterol) and increasing HDL (good cholesterol). This mineral is known to have anti-inflammatory properties, which could indirectly benefit heart health and cholesterol levels by improving overall cardiovascular function.
However, it's important to note that while magnesium can be a supportive element in a holistic approach to managing cholesterol, it should not be viewed as a standalone solution. Incorporating magnesium-rich foods, such as leafy greens, nuts, seeds, and whole grains, into a balanced diet is advisable. Moreover, those with high cholesterol should consult healthcare professionals for personalized advice and appropriate treatment options, including lifestyle changes and medications when necessary.
Based on user reviews, it appears that individuals taking this supplement for high cholesterol generally start to see improvements within a few weeks to a few months. One user mentioned that after just a few months of consistent use, their readings improved significantly, noting a drop in high blood pressure and improvements in cholesterol levels as well Read Review. Another user reported feeling the benefits, including normalization of their blood pressure and cholesterol levels, developing over a similar timeframe Read Review.
While specific timelines may vary based on individual health conditions and adherence to dosage, many users highlight seeing noticeable changes in their health metrics over a couple of months. It's essential to track your health alongside dietary changes and consult with a healthcare professional to gauge the full impact of the supplement on your cholesterol levels.
The evidence surrounding the effectiveness of magnesium-rich supplements and deep seawater for managing high cholesterol is promising but still under investigation. For instance, a study focused on individuals consuming deep seawater reported a significant decrease in total and LDL cholesterol levels, indicating its potential as a supplement for those struggling with high cholesterol [5]. Meanwhile, evidence from various animal studies suggests that magnesium compounds, such as magnesium chloride, might offer benefits for cholesterol and cardiovascular health although results vary [8].
Furthermore, in populations with specific health conditions, like chronic kidney disease, a nutraceutical combination that includes magnesium showed an 18.9% reduction in cholesterol levels [2]. Additionally, observational research indicated that higher magnesium intake could correlate with lower cholesterol and cardiovascular disease risk [3]. While these findings highlight a potential link between magnesium-rich supplements and cholesterol management, the specific mechanisms and efficacy in human populations require further exploration. Thus, while there’s encouraging scientific support, more comprehensive clinical studies are needed to conclusively establish these supplements as effective solutions for high cholesterol.
Based on user reviews, many individuals have reported a variety of notable improvements in their symptoms after taking this supplement. For instance, users have experienced significant relief from cramps and numbness, with one reviewer emphasizing that their treatment effectively eliminated their symptoms and even enhanced their mood and sleep quality after just a short duration of use Read Review. Additionally, several users have highlighted improvements in their cardiovascular health metrics, particularly blood pressure and cholesterol levels. One user noted a considerable drop in their blood pressure readings and a normalization of cholesterol and triglyceride levels after a few months of use Read Review.
Moreover, other users have praised the supplement for its non-fatiguing effects compared to conventional medications, indicating a smooth transition to better health management without the side effects commonly linked with prescription drugs Read Review. Anecdotal evidence suggests that while individual results can vary, many users have found the combination of ingredients to effectively support their heart health and improve their overall well-being.
Based on user reviews, several individuals have successfully combined this supplement with other dietary measures to manage high cholesterol and blood pressure. For instance, one user noted that taking this supplement alongside improved eating habits and exercise contributed to a slight reduction in their blood pressure readings Read Review. Another reviewer mentioned that the high-quality ingredients in the supplement positively impacted their cholesterol and triglyceride levels, highlighting its effectiveness when used as part of a broader health strategy Read Review.
Moreover, users reported that the inclusion of ingredients such as taurine, magnesium, and potassium not only aided in managing blood pressure but also played a vital role in heart and blood vessel health Read Review. This suggests a synergistic effect when combining the supplement with healthy lifestyle choices. Many users recommended this supplement for its supportive role in improving cardiovascular health, emphasizing the importance of a holistic approach to managing cholesterol levels effectively Read Review.
Users have reported varying experiences regarding the appropriate dose of magnesium for treating high cholesterol, often in combination with other health benefits. For example, one user mentioned that they and their spouse take two tablets before bed, indicating personal satisfaction with that dosage without directly linking it to cholesterol levels Read Review. Another user highlighted improvements in their cholesterol and triglyceride levels after starting magnesium in conjunction with managing their blood pressure, although the exact dosage wasn't specified Read Review.
Several reviews suggested that users felt significant health improvements even when they weren't adhering to the full recommended daily dosage. One user noted they weren't taking the full recommended amount but were still seeing slight reductions in blood pressure and presumably cholesterol levels Read Review. Overall, while a specific optimal dose for cholesterol management remains unclear from these reviews, users seem to benefit from regular intake, often coupled with lifestyle changes.
9
Blood pressure decrease
1 people found this helpful
My husband began using this supplement after hearing its benefits for reducing high blood pressure. His readings have improved from 148 to 125 after just a few months. The high-quality ingredients have made a significant positive impact, and we plan on purchasing more.
7.5
Reduced triglycerides
2 people found this helpful
I started this for my blood pressure, and positively, my cholesterol and triglyceride levels have also decreased alongside the blood pressure normalising. I'm thrilled with the results.
7.5
Effective heart support
18 people found this helpful
This dietary supplement has been exceptional for my health. The rapid absorption of magnesium aspartate and potassium has made a noticeable difference. After my course of treatment, the cramps and numbness in my hands vanished. My mood and sleep quality have improved too. This product effectively strengthens the cardiovascular system and can be safely taken without harming other organs. I highly recommend this high-quality supplement for anyone seeking heart health improvement.
7.5
Effective for BP
3 people found this helpful
I started taking this for my high blood pressure and have found it effective without causing fatigue, unlike prescription drugs. It was heartening to learn taurine aids in lowering blood pressure from my doctor. This product suits my needs perfectly.
6
Some improvement noted
3 people found this helpful
I have high blood pressure, and my previous prescription medication (lisinopril) caused me anxiety. So, I’ve gradually been reducing my dosage and focusing on better eating habits and more exercise. I needed an alternative to help manage it, so I tried NOW's Magnes & Potass. Although I haven’t been taking the full recommended daily dosage, I believe it helps reduce my readings slightly. The true effects of such supplements can be uncertain, but so far, I’ve noticed positive changes.
7.5
Lowered blood pressure
10 people found this helpful
Taurine, an amino acid in this product, has been beneficial for my and my daughter's high blood pressure. We're noticing improvements together; my blood pressure has normalised, and now I no longer need medication. The inclusion of magnesium and potassium also supports heart and blood vessel health effectively.
9
Cramps eliminated
4 people found this helpful
My wife and I take two tablets before bed. They effectively eliminate our cramps without relying on high-carb bananas. We highly recommend this approach!
9
Deep seawater aids cholesterol reduction
Drinking deep seawater decreases serum total and low-density lipoprotein-cholesterol in hypercholesterolemic subjects.
We explored how drinking deep seawater (DSW), rich in magnesium, impacts cholesterol levels in people with high cholesterol. In a study involving 42 volunteers, participants consumed 1050 mL of DSW, magnesium-fortified water, or reverse osmosis water daily for six weeks. The results were promising: those who drank DSW experienced a notable decrease in total cholesterol and low-density lipoprotein (LDL) cholesterol over time. Additionally, blood samples revealed that DSW also reduced markers of oxidative stress. This suggests that DSW may offer a valuable option for managing high cholesterol.
8
Magnesium chloride may lower cholesterol
Atherogenesis inhibition induced by magnesium-chloride fortification of drinking water.
We explored whether magnesium, specifically in the form of magnesium chloride, could help fight high cholesterol and atherosclerosis.
In a study with male mice, different concentrations of magnesium chloride were added to their drinking water, while they followed various diets.
We found that the higher concentration seemed to lower the extent of atherosclerosis significantly, along with reducing cholesterol levels after an initial stage.
However, overall blood lipid levels remained similar before and after the study, indicating mixed results in magnesium's effectiveness against high cholesterol.
7
RenaTris effectively lowers cholesterol
Cholesterol-Lowering Action of a Novel Nutraceutical Combination in Uremic Rats: Insights into the Molecular Mechanism in a Hepatoma Cell Line.
We investigated how a new nutraceutical combination, RenaTris, could affect cholesterol levels in uremic rats. In our study, uremic rats experienced a rise in cholesterol levels due to their high-phosphate diet.
Interestingly, the addition of RenaTris—including magnesium and other ingredients—resulted in a notable reduction of cholesterol by 18.9%.
While the treatment didn’t improve other health markers related to kidney function, it suggests a beneficial effect on cholesterol management, especially for patients with chronic kidney disease.
8
Magnesium helps reduce cholesterol risk
An inverse association between magnesium in 24-h urine and cardiovascular risk factors in middle-aged subjects in 50 CARDIAC Study populations.
We examined how magnesium levels in urine relate to cardiovascular disease risk factors, focusing on cholesterol and other health measures. In a large, diverse group of 4,211 participants from 50 countries, we found that higher urinary magnesium was linked to lower body mass index, blood pressure, and total cholesterol.
Notably, people with the highest magnesium levels experienced significantly lower risks for obesity and hypertension compared to those with the lowest levels. These findings suggest that increasing magnesium intake may have meaningful benefits for heart health.
References
Mohammed KA, Goji ADT, Tanko Y, Muhammed A, Salisu IA. Protective Effects of Magnesium Chloride on Liver Enzymes and Biomarkers of Oxidative Stress in high fat diet fed Rats. Niger J Physiol Sci. 2019;34:149.
Lupo MG, Biancorosso N, Brilli E, Tarantino G, Adorni MP, et al. Cholesterol-Lowering Action of a Novel Nutraceutical Combination in Uremic Rats: Insights into the Molecular Mechanism in a Hepatoma Cell Line. Nutrients. 2020;12. doi:10.3390/nu12020436
Yamori Y, Sagara M, Mizushima S, Liu L, Ikeda K, et al. An inverse association between magnesium in 24-h urine and cardiovascular risk factors in middle-aged subjects in 50 CARDIAC Study populations. Hypertens Res. 2015;38:219. doi:10.1038/hr.2014.158
Sheu MJ, Chou PY, Lin WH, Pan CH, Chien YC, et al. Deep sea water modulates blood pressure and exhibits hypolipidemic effects via the AMPK-ACC pathway: an in vivo study. Mar Drugs. 2013;11:2183. doi:10.3390/md11062183
Fu ZY, Yang FL, Hsu HW, Lu YF. Drinking deep seawater decreases serum total and low-density lipoprotein-cholesterol in hypercholesterolemic subjects. J Med Food. 2012;15:535. doi:10.1089/jmf.2011.2007
Song Y, Ridker PM, Manson JE, Cook NR, Buring JE, et al. Magnesium intake, C-reactive protein, and the prevalence of metabolic syndrome in middle-aged and older U.S. women. Diabetes Care. 2005;28:1438.
Tapola NS, Lyyra ML, Karvonen HM, Uusitupa MI, Sarkkinen ES. The effect of meat products enriched with plant sterols and minerals on serum lipids and blood pressure. Int J Food Sci Nutr. 2004;55:389.
Cohen H, Sherer Y, Shaish A, Shoenfeld Y, Levkovitz H, et al. Atherogenesis inhibition induced by magnesium-chloride fortification of drinking water. Biol Trace Elem Res. 2002;90:251.
Evans DA, Tariq M, Sujata B, McCann G, Sobki S. The effects of magnesium sulphate and EDTA in the hypercholesterolaemic rabbit. Diabetes Obes Metab. 2001;3:417.
Feng Z, Morton JD, Maes E, Kumar L, Serventi L. Proximate composition, peptide characterization and bioactive properties of faba bean blanching water. Food Res Int. 2025;200:115426. doi:10.1016/j.foodres.2024.115426
Wang DD, Li Y, Nguyen XT, Song RJ, Ho YL, et al. Dietary Sodium and Potassium Intake and Risk of Non-Fatal Cardiovascular Diseases: The Million Veteran Program. Nutrients. 2022;14. doi:10.3390/nu14051121
Moreira RS, Irigoyen MC, Capcha JMC, Sanches TR, Gutierrez PS, et al. Synthetic apolipoprotein A-I mimetic peptide 4F protects hearts and kidneys after myocardial infarction. Am J Physiol Regul Integr Comp Physiol. 2020;318:R529. doi:10.1152/ajpregu.00185.2019
Lee HY, Kim SY, Choi KJ, Yoo BS, Cha DH, et al. A Randomized, Multicenter, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and the Tolerability of a Triple Combination of Amlodipine/Losartan/Rosuvastatin in Patients With Comorbid Essential Hypertension and Hyperlipidemia. Clin Ther. 2017;39:2366. doi:10.1016/j.clinthera.2017.10.013
Toxqui L, Vaquero MP. An Intervention with Mineral Water Decreases Cardiometabolic Risk Biomarkers. A Crossover, Randomised, Controlled Trial with Two Mineral Waters in Moderately Hypercholesterolaemic Adults. Nutrients. 2016;8. doi:10.3390/nu8070400